Dofetilide*BC

  • Tikosyn
  • Dosage: 125-500 mg q12h
  • Formulations: C 125, 250, 500
  • Comments (Metabolism): May prolong QT interval on EKG and requires initiation in hospital due to potential for torsades de pointes ventricular tachycardia; reduce dose if CrCl is 20-59 mL/min, contraindicated if CrCl <20 mL/min

Notes:

* following a drug name indicates the drug is available as a generic formulation.

BC following a drug name indicates the drug is listed in the 2023 American Geriatrics Society Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults.

K = renal elimination; L = hepatic elimination


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